Duoval/Duoval Max Adverse Reactions

Headache, upper respiratory infection, sinusitis, back pain and chest pain occurred at a more than 2% rate but at about the same incidence in placebo and valsartan-hydrochlorothiazide patients. Dose related orthostatic effects were seen in less than 1% of patients. A dose related increase in the incidence of dizziness was observed in patients treated with (Valsartan + hydrochlorothiazide) Duoval from 80/12.5 mg (6%) to 160/25 mg (16%). Other adverse experiences that have been reported with valsartan-hydrochlorothiazide (>0.2% of valsartan-hydrochlorothiazide patients in controlled trials) without regard to causality are listed as follows: Body as a whole: Allergic reaction, anaphylaxis, asthenia, and dependent edema.
Cardiovascular: Palpitations, syncope, and tachycardia.
Dermatologic: Flushing, rash, sunburn and increased sweating.
Digestive: Increased appetite, constipation, dyspepsia, flatulence, dry mouth, nausea abdominal pain, and vomiting.
Metabolic: Dehydration and gout.
Musculoskeletal: Arthralgia, muscle cramps, muscle weakness, arm pain, and leg pain.
Neurologic and Psychiatric: Anxiety, depression, insomnia, decreased libido, paresthesia, and somnolence.
Respiratory: Bronchospasm, dyspnea, and epistaxis.
Urogenital: Dysuria, impotence, micturition frequency, and urinary tract infection.